Our review paper “The Centrality of RNA for Engineering Gene Expression” is out! The review covers the ethos of the lab, and has three main sections: an update of all the known natural and synthetic RNA-based regulatory mechanisms out there, an outline of computational RNA structure prediction tools and how they have facilitated RNA engineering, and a perspective of how next-generation sequencing technologies that perform cell-wide characterization of RNA properties will transform synthetic biology.
We covered a lot of ground, but it is meant to be a launching point for those uninitiated to the power of RNA, as well as have interesting new details for those already converted. We also designed Figure 2 to be able to be conveniently printed out and hung up on the wall as a one-stop shop for RNA-based mechanisms!
Congratulations to the whole lab – we all contributed to this review and it is one of the few papers where the entire lab is an author!
You can read the paper for free here – http://onlinelibrary.wiley.com/doi/10.1002/biot.201300018/abstract