Cell-free biosensors: where have we been and where do we need to go?

A. Arce, D. M. Brown, H. A. Demissie, S. Feng, M. Naji, J. B. Lucks. Current Opinion in Biotechnology (2026). doi: 10.1016/j.copbio.2026.103451.
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Here, we review the key technological advances of cell-free biosensors over the last five years and suggest a future path of technology development, including interfacing with circuits, devices, and materials that are becoming part of the next generation of biosensors.

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