Daily Archives: April 10, 2017


Eric & Kyle’s paper on biotin-streptavidin roadblocks for Cotranscriptional SHAPE-Seq is now online at NAR!

Eric and Kyle’s paper “Distributed biotin-streptavidin transcription roadblocks for mapping cotranscriptional RNA folding” is now online at Nucleic Acids Research! This work makes cotranscriptional SHAPE-Seq even easier and more accessible by developing a “one-pot” synthesis for roadblocking DNA templates and uncovers important details about how collision with different transcription roadblocks can […]