Cameron’s review on engineered protein machines is out!

Cameron’s review “Engineered Protein Machines: Emergent Tools for Synthetic Biology” is out in the inaugural edition of Cell Chemical Biology! This is a great summary of recent work in synthetic biology to make ‘orthogonal’ versions of core cellular protein machines – from polymerases all the way to ribosomes. By acting independently from the native machinery, orthogonal protein machines allow two important advances: 1) they can allow synthetic systems to be regulated independently of host resources to decouple and simplify the engineering of these systems, and 2) they can be further engineered themselves. Cameron did a great job of reviewing the current state of the art in this exciting area and outlining all the advances that will be enabled by these breakthroughs!

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