Katherine and Matthew have joined the lab from the Biochemistry, Molecular and Cellular Biology program – welcome Katherine and Mathew!
Category Archives: News
Our 11th Paper is Published with Trello!
Anyone that has spent any time with us knows how much we love Trello. If you haven’t heard of it, it is a lightweight team management tool that we use throughout the lab – from writing papers and grants, to managing lab orders and our lab safety system. We’ve even used it extensively as aContinue reading “Our 11th Paper is Published with Trello!”
Introducing Dr. Watters!
Dr. Watters next heads to Jennifer Doudna’s lab – go Dr. Watters!
Kyle Wins Austin Hooey Graduate Award
Kyle is the recipient of an Austin Hooey Graduate Award. The Hooey award is the highest honor that CBE bestows on graduate students, and recognizes those students who have demonstrated the highest research quality and productivity, and who have demonstrated a track record of service to their research group, department, and community. The Hooey award is givenContinue reading “Kyle Wins Austin Hooey Graduate Award”
Alex wins the CBE 2016 Outstanding Scholar Award!
Congratulations Alex for winning the CBE 2016 Outstanding Scholar Award! The award recognizes Alex’s outstanding research accomplishments as an undergraduate and his transition to industry where he will join Caribou Biosciences. Congratulations Alex!
Our paper on the design principles of transcriptional attenuators is out!
Melissa, Kyle, Tim and Paul’s paper “Using in-cell SHAPE-Seq and simulations to probe structure-function design principles of RNA transcriptional regulators” is out in RNA! This paper marks an important milestone for us – its our first manuscript on using information gleaned from in-cell SHAPE-Seq experiments to inform the design of new RNA regulators! This project startedContinue reading “Our paper on the design principles of transcriptional attenuators is out!”
Spats v1.0 is released!
Spats v1.0.0 is an update to the Spats pipeline for processing Next-Generation Sequencing Reads as part of SHAPE-Seq experiments. The major difference between v0.8.0 and v1.0.0 is the migration to the cutadapt utility for removing adapter sequences from the fastxtoolkit. This release still relies on fastx_revcomp, but the code is structured to completely move away fromContinue reading “Spats v1.0 is released!”
Our methods paper on SHAPE-Seq v2.1 is out!
Kyle, Angela, Eric and Alex’s paper “Characterizing RNA structures in vitro and in vivo with selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)” is out in Methods! This is a very comprehensive manuscript, outlining the necessary background for understanding chemical probing of RNA structure – from the experiments that can generate the data all theContinue reading “Our methods paper on SHAPE-Seq v2.1 is out!”
Our review on RNA Systems Biology is out!
Eric, Kyle and David’s review “RNA systems biology: uniting functional discoveries and structural tools to understand global roles of RNAs” is out in Current Opinion in Biotechnology! In this review, we outline the case that the time is right for a systems-level study of RNA structure and function – partly because of the rapid paceContinue reading “Our review on RNA Systems Biology is out!”
Cameron’s review on engineered protein machines is out!
Cameron’s review “Engineered Protein Machines: Emergent Tools for Synthetic Biology” is out in the inaugural edition of Cell Chemical Biology! This is a great summary of recent work in synthetic biology to make ‘orthogonal’ versions of core cellular protein machines – from polymerases all the way to ribosomes. By acting independently from the native machinery,Continue reading “Cameron’s review on engineered protein machines is out!”
Lucks Laboratory 