We have an influx of new Lucks Lab members! Welcome Angela, Aron, Jane, Yan and Raashed!
Category Archives: News
Another Great Year at CSHL SynBio
We had another fantastic year at the Cold Spring Harbor Laboratory Synthetic Biology summer course! Led by James (universally voted a Rock STAR scientist by everyone at the course), we successfully delivered a thrilling module on characterizing genetic circuitry using cell-free TX-TL reactions. Actually I can’t thank James enough for all the hard work both beforeContinue reading “Another Great Year at CSHL SynBio”
A Renaissance in RNA Synthetic Biology
A renaissance in RNA synthetic biology: new mechanisms, applications and tools for the future is out in Current Opinion in Chemical Biology! James, Kyle and Melissa did a fantastic job making our case for why we think we are in a renaissance in RNA synthetic biology right now. In the review, we go over the latestContinue reading “A Renaissance in RNA Synthetic Biology”
Improving STARs with Rational RNA Engineering Strategies
Our paper on improving Small Transcription Activating RNAs with Rational RNA Engineering Strategies is out in Biotechnology and Bioengineering! In this paper, Sarai, James, Sitara and Rebecca outline several different strategies for improving the fold activation of weak STARs, including promoter tuning and RNA stabilization strategies. We hope this helps others use STARs in theirContinue reading “Improving STARs with Rational RNA Engineering Strategies”
Our RNA Circuitry Modeling Paper is Out!
Our paper on Generating effective models and parameters for RNA genetic circuits is out in ACS Synthetic Biology. In this paper, Chelsea developed a simplified ODE model to model the dynamics of RNA genetic circuits. These ‘effective’ models essentially course grain a lot of the biochemical details of gene expression into simple mass-action kinetics thatContinue reading “Our RNA Circuitry Modeling Paper is Out!”
Our TX-TL Methods Paper is Out!
We were recently invited to prepare a paper for the journal Methods about using cell-free transcription-translation reactions (TX-TL) to characterize genetic circuits. We immediately joined forces with Vincent Noireaux’s and Richard Murray’s groups and had a lot of fun putting this together! What started out as a brief intro to the basics behind TX-TL turned intoContinue reading “Our TX-TL Methods Paper is Out!”
Congratulations to our Graduates!
Congratulations Rebecca, Melissa, Misha, Tim, Ray and Sitara (not pictured)! Melissa is our first Dr. from the group, and will be joining Jim Collin’s lab at MIT in the Fall as a post-doctoral researcher. Also staying on the East Coast, Misha will be headed to join a consulting firm in New York City. On theContinue reading “Congratulations to our Graduates!”
ACS SynBio Special Issue: RNA Synthetic Biology Shout Outs
This month, the issue of ACS Synthetic Biology is devoted to RNA Synthetic Biology. In addition check out our shout outs! Melissa and James are featured in Introducing Our Authors. Justin Gallivan has a very nice perspective called RNA Synthetic Biology: From the Test Tube and Back Again. It includes a nice shout out toContinue reading “ACS SynBio Special Issue: RNA Synthetic Biology Shout Outs”
We got the ACS Syn Bio Cover!
Congratulations Dr. Takahashi!
Melissa -> Dr. Takahashi!
Lucks Laboratory 