Spats v1.0.0 is an update to the Spats pipeline for processing Next-Generation Sequencing Reads as part of SHAPE-Seq experiments. The major difference between v0.8.0 and v1.0.0 is the migration to the cutadapt utility for removing adapter sequences from the fastxtoolkit. This release still relies on fastx_revcomp, but the code is structured to completely move away fromContinue reading “Spats v1.0 is released!”
Author Archives: jblucks
Our methods paper on SHAPE-Seq v2.1 is out!
Kyle, Angela, Eric and Alex’s paper “Characterizing RNA structures in vitro and in vivo with selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)” is out in Methods! This is a very comprehensive manuscript, outlining the necessary background for understanding chemical probing of RNA structure – from the experiments that can generate the data all theContinue reading “Our methods paper on SHAPE-Seq v2.1 is out!”
Our review on RNA Systems Biology is out!
Eric, Kyle and David’s review “RNA systems biology: uniting functional discoveries and structural tools to understand global roles of RNAs” is out in Current Opinion in Biotechnology! In this review, we outline the case that the time is right for a systems-level study of RNA structure and function – partly because of the rapid paceContinue reading “Our review on RNA Systems Biology is out!”
Cameron’s review on engineered protein machines is out!
Cameron’s review “Engineered Protein Machines: Emergent Tools for Synthetic Biology” is out in the inaugural edition of Cell Chemical Biology! This is a great summary of recent work in synthetic biology to make ‘orthogonal’ versions of core cellular protein machines – from polymerases all the way to ribosomes. By acting independently from the native machinery,Continue reading “Cameron’s review on engineered protein machines is out!”
Julius joins Nucleic Acids Research Editorial Board!
Julius was recently invited to be a member of the Editorial Board of Nucleic Acids Research. Nucleic Acids Research is a preeminent journal featuring cutting edge research into the physical, chemical, biochemical and biological aspects of nucleic acids and the protein machinery that interacts with them in the cell. Its long tradition of excellence hasContinue reading “Julius joins Nucleic Acids Research Editorial Board!”
Congratulations Karl and Chelsea on passing their exams!
Chelsea recently passed her A exam and Karl recently passed his masters exam – congratulations! Karl will be joining Merk back in Ireland soon – we’ll miss you Karl!
Julius receives College Teaching Award
Julius was the recent recipient of the Mr. and Mrs. Richard F. Tucker `50 Excellence in Teaching Award, the highest award for teaching in the Cornell College of Engineering. The award recognizes Julius’ excellence and achievements in teaching Heat and Mass Transfer, and his co-creation of ChemE 7770 “Advanced Principles of Biomolecular Engineering”, one ofContinue reading “Julius receives College Teaching Award”
Professor Venkat Gopalan Visits the Lab!
We were recently delighted to host Professor Venkat Gopalan from Ohio State University in the lab! Professor Gopalan studies RNase P, an ancient RNA that catalyzes a key reaction required for all life. It’s discovery by Sidney Altman earned him a Nobel Prize in Chemistry 1989 for the discovery that RNA molecules can catalyze chemical reactions. After trainingContinue reading “Professor Venkat Gopalan Visits the Lab!”
Sarai’s Paper Featured in B&B Spotlight!
Sarai’s paper was recently featured in a Biotechnology and Bioengineering spotlight Shining RNA STAR power on bacterial gene expression. Each issue of B&B features four spotlights highlighting the most exciting work in the journal. It’s quite an honor! Congratulations Sarai, James, Sitara and Rebecca!
Get our plasmids from the Lucks Lab AddGene Page!
The Lucks Lab now officially has an Addgene page! Addgene is a non-profit plasmid repository that promotes sharing of life sciences research materials through their distribution system. We have greatly benefited from easy access to the explosion of molecular tools out there which has really helped us accelerate our research! If you have never heard ofContinue reading “Get our plasmids from the Lucks Lab AddGene Page!”
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